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What is Reactome ?
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VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]
Stable Identifier
R-GGA-4420101
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
AXL autophosphorylates on Y779 and Y821 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
CDC42:GTP binds PAK2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
CRK binds BCAR1 and or PXN (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
DOCK180:ELMO binds CRK (Gallus gallus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
FYN autophosphorylates (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
FYN phosphorylates PAK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
HSP90AA1 binds p-6Y-VEGFR2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PAK2 autophorylates (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PAK2 binds NCK (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PTK2 autophosphorylates (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PTK2beta binds alphaVbeta3 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
PXN binds p-6Y,S732-PTK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
Phosphorylation of SRC-1 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SRC-1 binds p-Y397-PTK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SRC-1 phosphorylates PTK2-beta (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SRC-1 phosphorylates SHB (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SRC-1 phosphorylates p-Y397-PTK2 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
Src kinases phosphorylate VAV (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFR2 autophosphorylates (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFR2 mediated cell proliferation (Gallus gallus)
PLCG1 disassociates from VEGFR2 and translocate to PM (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
SFKs phosphorylate PLCG1 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds PLCG1 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds FYN (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds NCK (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds SH2D2A (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds SHB (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-6Y-VEGFR2 binds SHC-transforming protein 2 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-AXL binds PI3K (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
p38 MAPK activation by VEGFR (Gallus gallus)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
p-6Y-VEGFR2 dimer [plasma membrane]
(Gallus gallus)
VEGFA-165 dimer [extracellular region]
(Gallus gallus)
Participates
as an input of
p-6Y-VEGFR2 binds SHC-transforming protein 2 (Gallus gallus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Gallus gallus)
p-6Y-VEGFR2 binds SHB (Gallus gallus)
p-6Y-VEGFR2 binds NCK (Gallus gallus)
p-6Y-VEGFR2 binds SH2D2A (Gallus gallus)
p-6Y-VEGFR2 binds PLCG1 (Gallus gallus)
as a component of
VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] (Gallus gallus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
as an output of
PLCG1 disassociates from VEGFR2 and translocate to PM (Gallus gallus)
VEGFR2 autophosphorylates (Gallus gallus)
Inferred From
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]
(Homo sapiens)
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