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phospho-IKBKE [cytosol]
Stable Identifier
R-GGA-450278
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
p-S172-IKBKE, E1BV51
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF(TICAM1)-mediated TLR4 signaling (Gallus gallus)
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon (Gallus gallus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Gallus gallus)
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
phospho-IKBKE [cytosol] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Gallus gallus)
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
phospho-IKBKE [cytosol] (Gallus gallus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Gallus gallus)
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
phospho-IKBKE [cytosol] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Gallus gallus)
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
phospho-IKBKE [cytosol] (Gallus gallus)
Recruitment of TBK1/IKK epsilon to K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR4 followed by their phosphorylation (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Gallus gallus)
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
phospho-IKBKE [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BV51
Gene Names
IKBKE
Reference Genes
ENSEMBL:ENSGALG00000013356
Other Identifiers
430480
GO:0000166
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004704
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0006464
GO:0006468
GO:0006950
GO:0007165
GO:0007252
GO:0008150
GO:0008219
GO:0008384
GO:0008630
GO:0010884
GO:0016301
GO:0016605
GO:0016740
GO:0018105
GO:0019899
GO:0030234
GO:0031625
GO:0031966
GO:0034340
GO:0035456
GO:0036435
GO:0038061
GO:0042802
GO:0043123
GO:0043167
GO:0043226
GO:0060340
GO:0098586
GT_A_87_P063586
GgaAffx.8507.1.S1_at
Participates
as a member of
activated TBK1/IKK epsilon [cytosol] (Gallus gallus)
Other forms of this molecule
phospho-IKBKE [nucleoplasm]
phospho-IKBKE [nucleoplasm]
IKBKE [cytosol]
Inferred From
p-S172-IKBKE [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 172 (in Homo sapiens)
Coordinate
172
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
OpenTargets
ENSG00000263528
Ensembl
ENSGALG00000013356
,
ENSGALT00000021795
,
ENSGALP00000021757
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