activated MEK2 phosphorylates ERK2

Stable Identifier
R-GGA-451516
Type
Reaction
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
Summation

Chicken ERK2 shares 99% of amino acid sequence identity with human and mouse ERK2. Multiple sequence alignment of human, mouse and chicken ERK2 by ClustalW allowed to predict that the following chicken residues are involved in chicken ERK2 activation: Thr193 and Tyr195 corresponding to mammalian Thr185 and Tyr187.

Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of phospho MEK2 : ERK2 [cytosol]
Physical Entity
Activity
Inferred From