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BIRC3 [cytosol]
Stable Identifier
R-GGA-50845
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
A0A140T8H6
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
TNFR2 non-canonical NF-kB pathway (Gallus gallus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Gallus gallus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Gallus gallus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TRAF3 binds BAFFR:BAFF (Gallus gallus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TRAFs bind RANK:RANKL (Gallus gallus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Gallus gallus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Gallus gallus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Gallus gallus)
TRAF2:cIAP1,2 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
IKK complex recruitment mediated by RIP1 (Gallus gallus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Gallus gallus)
RIP1 ubiqutin ligases [cytosol] (Gallus gallus)
c-IAP2:UBE2D [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
USP19 binds HIF1A,BIRC2,BIRC3 (Gallus gallus)
HIF1A,BIRC2,BIRC3 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
USP19:HIF1A,BIRC2,BIRC3 [cytosol] (Gallus gallus)
HIF1A,BIRC2,BIRC3 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Regulated Necrosis (Gallus gallus)
RIPK1-mediated regulated necrosis (Gallus gallus)
Regulation of necroptotic cell death (Gallus gallus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
K63polyUb-RIPK1 is deubiquitinated (Gallus gallus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Gallus gallus)
TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] (Gallus gallus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Gallus gallus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Gallus gallus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Gallus gallus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNFR1-induced NF-kappa-B signaling pathway (Gallus gallus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A140T8H6
Reference Genes
ENSEMBL:ENSGALG00000017186
Participates
as a member of
HIF1A,BIRC2,BIRC3 [cytosol] (Gallus gallus)
cIAP1,2 [cytosol] (Gallus gallus)
BIRC2,3,4 [cytosol] (Gallus gallus)
as a component of
c-IAP2:UBE2D [cytosol] (Gallus gallus)
Other forms of this molecule
K63polyUb-BIRC3 [cytosol]
K63polyUb-BIRC2 [cytosol]
BIRC2(1-372) [cytosol]
BIRC2(373-618) [cytosol]
K48pUb-BIRC2 [cytosol]
K48pUb-BIRC3 [cytosol]
BIRC2 [cytosol]
Inferred From
BIRC3 [cytosol]
(Homo sapiens)
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