Reactome | RAD23B [nucleoplasm]

RAD23B [nucleoplasm]

Stable Identifier

R-GGA-62590

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

F1N9B7

Locations in the PathwayBrowser

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DNA Repair (Gallus gallus)

- Nucleotide Excision Repair (Gallus gallus)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Gallus gallus)
    - DNA Damage Recognition in GG-NER (Gallus gallus)
      - PARP1 or PARP2 PARylates DDB2 and autoPARylates (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - PARP1 or PARP2 binds DDB2 at GG-NER site (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - UV-DDB ubiquitinates XPC (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - XPC binds RAD23 and CETN2 (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Gallus gallus)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Gallus gallus)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
    - Formation of Incision Complex in GG-NER (Gallus gallus)
      - CHD1L is recruited to GG-NER site (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - RNF111 ubiquitinates SUMOylated XPC (Gallus gallus)
        
        Ub,SUMO,K63polyUb:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub,SUMO:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - Recruitment of XPA and release of CAK (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - SUMOylation of XPC (Gallus gallus)
        
        Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub,SUMO:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
      - TFIIH binds GG-NER site to form a verification complex (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Gallus gallus)
        
        RAD23 [nucleoplasm] (Gallus gallus)
        
        RAD23B [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:F1N9B7

Reference Genes

ENSEMBL:ENSGALG00000015540

Participates

as a member of

Other forms of this molecule

RAD23B [cytosol]

Inferred From

RAD23B [nucleoplasm] (Homo sapiens)

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