Reactome | RPS28 [cytosol]

RPS28 [cytosol]

Stable Identifier

R-GGA-72365

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPS28, A0A3Q2U825

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS28 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS28 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS28 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS28 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        40S ribosomal complex [cytosol] (Gallus gallus)
        
        RPS28 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2U825

Gene Names

RPS28

Reference Genes

BioGPS Gene:768930 RPS28

ENSEMBL:ENSGALG00000049538

ENSEMBL:ENSGALG00010028463.1 RPS28

KEGG Gene (Gallus gallus):768930 RPS28

Monarch:768930 RPS28

NCBI Gene:768930 RPS28

Reference Transcript

RefSeq:NM_001302177.1 RPS28

Other Identifiers

768930

GO:0000028

GO:0002181

GO:0003735

GO:0005198

GO:0005829

GO:0005840

GO:0006364

GO:0006412

GO:0022627

GO:0030490

GO:0032040

GO:0042254

GO:0042274

GO:0042788

GO:0043226

GO:0045202

GO:0065003

GT_A_87_P061646

Gga.4500.1.S1_at

Gga.4500.1.S2_at

Participates

as a component of

40S ribosomal complex [cytosol] (Gallus gallus)

Other forms of this molecule

RPS28 [nucleoplasm]

Inferred From

RPS28 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001289106.1

OpenTargets

ENSG00000233927

Ensembl

ENSGALT00010068927, ENSGALP00010042369, ENSGALG00010028463

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