Reactome | RPL37 [cytosol]

RPL37 [cytosol]

Stable Identifier

R-GGA-72466

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPL37, E1C810

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL37 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL37 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL37 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL37 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL37 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1C810

Gene Names

RPL37

Reference Genes

BioGPS Gene:427186 RPL37

ENSEMBL:ENSGALG00000014833

ENSEMBL:ENSGALG00010013438.1 RPL37

KEGG Gene (Gallus gallus):427186 RPL37

Monarch:427186 RPL37

NCBI Gene:427186 RPL37

Reference Transcript

RefSeq:NM_001122763.1 RPL37

Other Identifiers

427186

GO:0003723

GO:0003735

GO:0005198

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0019843

GO:0022625

GO:0043226

GO:0045202

GO:0046872

GO:1990904

GT_A_87_P022373

GT_A_87_P294403

GT_Sp_Chicken_CN217041_758

Gga.3410.1.S1_at

Participates

as a component of

Inferred From

RPL37 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001116235.1

OpenTargets

ENSG00000145592

Ensembl

ENSGALT00010032339, ENSGALT00010032343, ENSGALP00010019118, ENSGALG00010013438, ENSGALP00010019121