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TXN [cytosol]
Stable Identifier
R-GGA-73668
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
2xHC-TXN, P08629
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular Senescence (Gallus gallus)
Oxidative Stress Induced Senescence (Gallus gallus)
ROS oxidize thioredoxin and activate MAP3K5 (Gallus gallus)
TXN [cytosol] (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)
TXN [cytosol] (Gallus gallus)
thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Gallus gallus)
TXN [cytosol] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)
TXN [cytosol] (Gallus gallus)
thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Gallus gallus)
TXN [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Gallus gallus)
Inflammasomes (Gallus gallus)
The NLRP3 inflammasome (Gallus gallus)
ROS oxidize thioredoxin (Gallus gallus)
TXN [cytosol] (Gallus gallus)
Metabolism (Gallus gallus)
Metabolism of nucleotides (Gallus gallus)
Interconversion of nucleotide di- and triphosphates (Gallus gallus)
thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Gallus gallus)
TXN [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Protein repair (Gallus gallus)
MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Gallus gallus)
TXN [cytosol] (Gallus gallus)
MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Gallus gallus)
TXN [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:P08629
Gene Names
TXN
Reference Genes
BioGPS Gene:396437 TXN
ENSEMBL:ENSGALG00000015704
ENSEMBL:ENSGALG00010005495.1 TXN
ENSEMBL:ENSGALG00015028633 TXN
KEGG Gene (Gallus gallus):396437 TXN
Monarch:396437 TXN
NCBI Gene:396437 TXN
Reference Transcript
RefSeq:NM_205453.1 TXN
Other Identifiers
396437
GO:0003824
GO:0005576
GO:0005634
GO:0005737
GO:0009314
GO:0015035
GO:0016491
GO:0043226
GO:0043388
GO:0140096
GT_A_87_P053701
GT_A_87_P243763
GT_Xhyb_Chicken_CN218997_1260
Gga.4041.1.S1_a_at
Participates
as an output of
MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Gallus gallus)
MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Gallus gallus)
PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)
ROS oxidize thioredoxin (Gallus gallus)
ROS oxidize thioredoxin and activate MAP3K5 (Gallus gallus)
as an input of
thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Gallus gallus)
Other forms of this molecule
TXN [cytosol]
Inferred From
2xHC-TXN [cytosol]
(Homo sapiens)
Modified Residues
Name
Intra-chain Crosslink via L-cystine (cross-link) at 32 and 35 (in Homo sapiens)
Coordinate
32
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Cross References
RefSeq
NP_990784.1
OpenTargets
ENSG00000136810
Ensembl
ENSGALT00010013138
,
ENSGALG00010005495
,
ENSGALP00010007700
PRO
P08629
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