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SHC1 [cytosol]
Stable Identifier
R-GGA-74680
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SHC1, A0A1D5NYP8
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
RET signaling (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 in the RET complex is phosphorylated (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
Tie2 Signaling (Gallus gallus)
Interaction of Tie2 and Shc1 (Gallus gallus)
ANGPT1:p-5Y,S119-TEK:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Platelet activation, signaling and aggregation (Gallus gallus)
Platelet Aggregation (Plug Formation) (Gallus gallus)
Integrin signaling (Gallus gallus)
Activated integrin alphaIIb beta3 binds SHC1 (Gallus gallus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Gallus gallus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Gallus gallus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Integrin signaling (Gallus gallus)
Activated integrin alphaIIb beta3 binds SHC1 (Gallus gallus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Gallus gallus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Gallus gallus)
ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
MMPs cleave HB-EGF (Gallus gallus)
ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
SHC1 events in EGFR signaling (Gallus gallus)
SHC1 binds to the phosphorylated EGF receptor:ligand complex (Gallus gallus)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 phosphorylation by phosphorylated EGFR (Gallus gallus)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by ERBB2 (Gallus gallus)
SHC1 events in ERBB2 signaling (Gallus gallus)
SHC1 phosphorylation by ERBB2 heterodimers (Gallus gallus)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by ERBB4 (Gallus gallus)
SHC1 events in ERBB4 signaling (Gallus gallus)
Phosphorylation of SHC1 by ERBB4 homodimers (Gallus gallus)
SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 binds P-ERBB4 isoform dimers (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by Insulin receptor (Gallus gallus)
Insulin receptor signalling cascade (Gallus gallus)
Binding of SHC1 to insulin receptor (Gallus gallus)
Insulin:p-6Y-Insulin receptor:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Phosphorylation of SHC1 (Gallus gallus)
Insulin:p-6Y-Insulin receptor:SHC1 [plasma membrane] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Signaling by LTK (Gallus gallus)
Active LTK receptor binds SHC1 (Gallus gallus)
Active LTK:SHC1 [plasma membrane] (Gallus gallus)
SHC1-1,SHC1-2,SHC1-3 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
SHC1-1,SHC1-2,SHC1-3 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
Active LTK receptor phosphorylates SHC1 (Gallus gallus)
Active LTK:SHC1 [plasma membrane] (Gallus gallus)
SHC1-1,SHC1-2,SHC1-3 [cytosol] (Gallus gallus)
SHC1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5NYP8
Gene Names
SHC1
Reference Genes
BioGPS Gene:395934 SHC1
ENSEMBL:ENSGALG00000039775
ENSEMBL:ENSGALG00010027922.1 SHC1
KEGG Gene (Gallus gallus):395934 SHC1
Monarch:395934 SHC1
NCBI Gene:395934 SHC1
Reference Transcript
RefSeq:NM_001293280.2 SHC1
Other Identifiers
395934
GO:0001525
GO:0001784
GO:0005068
GO:0005158
GO:0005159
GO:0005168
GO:0005886
GO:0006351
GO:0006355
GO:0007010
GO:0007155
GO:0007173
GO:0007507
GO:0008286
GO:0012501
GO:0023052
GO:0030036
GO:0030971
GO:0035556
GO:0042127
GO:0042742
GO:0043066
GO:0043410
GO:0045892
GO:0045893
GO:0046875
GO:0048009
GO:0048408
GO:0048856
GO:0060090
GO:0070374
GO:0071363
GO:0098542
GO:0098609
GO:0110165
GT_A_87_P037982
GT_A_87_P088641
Gga.2219.1.S1_at
GgaAffx.8748.1.S1_at
Participates
as an input of
Activated integrin alphaIIb beta3 binds SHC1 (Gallus gallus)
Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Gallus gallus)
Interaction of Tie2 and Shc1 (Gallus gallus)
Binding of SHC1 to insulin receptor (Gallus gallus)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Gallus gallus)
SHC1 binds P-ERBB4 isoform dimers (Gallus gallus)
SHC1 binds to the phosphorylated EGF receptor:ligand complex (Gallus gallus)
as a component of
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Gallus gallus)
ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] (Gallus gallus)
ANGPT1:p-5Y,S119-TEK:SHC1 [plasma membrane] (Gallus gallus)
Insulin:p-6Y-Insulin receptor:SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Gallus gallus)
SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Gallus gallus)
as a candidate of
SHC1-1,SHC1-2,SHC1-3 [cytosol] (Gallus gallus)
Other forms of this molecule
SHC1 [plasma membrane]
SHC1 [plasma membrane]
SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
Inferred From
SHC1 [cytosol]
(Homo sapiens)
SHC1-1 [cytosol]
(Homo sapiens)
SHC1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001280209.1
OpenTargets
ENSG00000160691
Ensembl
ENSGALT00010067680
,
ENSGALG00010027922
,
ENSGALP00010041423
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