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FBXL8 [cytosol]
Stable Identifier
R-GGA-8850912
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
FBXL8, F1NNN0
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Gallus gallus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
SCF E3 ubiquitin ligase [cytosol] (Gallus gallus)
F-box protein [cytosol] (Gallus gallus)
FBXL8 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NNN0
Gene Names
FBXL8
Reference Genes
BioGPS Gene:415701 FBXL8
ENSEMBL:ENSGALG00000003201
ENSEMBL:ENSGALG00010024699.1 FBXL8
KEGG Gene (Gallus gallus):415701 FBXL8
Monarch:415701 FBXL8
NCBI Gene:415701 FBXL8
Reference Transcript
RefSeq:NM_001277684.1 FBXL8
RefSeq:XM_015279146.1 FBXL8
RefSeq:NM_001277683.1 FBXL8
Other Identifiers
415701
GO:0005515
GO:0019005
GO:0030163
GO:0031146
GT_A_87_P021534
GT_A_87_P074721
GT_A_87_P116078
Gga.9954.1.S1_at
Participates
as a member of
F-box protein [cytosol] (Gallus gallus)
Inferred From
FBXL8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001264613.1
,
XP_015134632.1
,
NP_001264612.1
OpenTargets
ENSG00000135722
Ensembl
ENSGALP00010037056
,
ENSGALG00010024699
,
ENSGALT00010060296
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