Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CUL1 [cytosol]
Stable Identifier
R-GGA-8952519
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
G76-NEDD8-K720-CUL1, A0A1D5P2L3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Gallus gallus)
CUL1 [cytosol] (Gallus gallus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Gallus gallus)
CUL1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5P2L3
Gene Names
CUL1
Reference Genes
BioGPS Gene:420783 CUL1
ENSEMBL:ENSGALG00000036941
KEGG:gga:420783 CUL1
Monarch:420783 CUL1
NCBI Entrez Gene:420783 CUL1
UCSC:A0A1D5P2L3 CUL1
Reference Transcript
RefSeq:XM_040664518.2 CUL1
RefSeq:XM_040696453.2 CUL1
RefSeq:XM_040664521.2 CUL1
RefSeq:XM_040664519.2 CUL1
RefSeq:XM_015275907.4 CUL1
RefSeq:XM_418878.8 CUL1
Other Identifiers
420783
GO:0000045
GO:0005886
GO:0006511
GO:0006513
GO:0006915
GO:0007040
GO:0008283
GO:0009887
GO:0010507
GO:0010508
GO:0016567
GO:0019005
GO:0030163
GO:0030674
GO:0031146
GO:0031461
GO:0031625
GO:0031669
GO:0034599
GO:0038202
GO:0043123
GO:0043124
GO:0043161
GO:0060090
GO:0070936
GO:0140374
GO:0160072
GO:1904037
GO:1904262
GO:1990452
GT_A_87_P034627
GT_Sp_Chicken_CN224679_4628
Gga.16583.1.S1_at
GgaAffx.23892.1.S1_s_at
Participates
as a component of
NEDD8-CRL1 E3 ligase complex [cytosol] (Gallus gallus)
Other forms of this molecule
CUL1 [nucleoplasm]
CUL1 [cytosol]
Inferred From
G76-NEDD8-K720-CUL1 [cytosol]
(Homo sapiens)
Modified Residues
Name
neddylated lysine (monoNEDD8 [cytosol]) at 720 (in Homo sapiens)
Coordinate
720
Modification
monoNEDD8 [cytosol]
PsiMod Name
neddylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein.
Cross References
RefSeq
XP_040520453.1
,
XP_040520452.1
,
XP_040520455.1
,
XP_040552387.1
,
XP_418878.3
,
XP_015131393.1
ENSEMBL
ENSGALT00010019850
,
ENSGALP00010011398
,
ENSGALG00010008300
© 2025
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text