Reactome | phospho-CASP9 [cytosol]

phospho-CASP9 [cytosol]

Stable Identifier

R-GGA-9627087

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

p-T125-CASP9(1-416), F1NL59

Locations in the PathwayBrowser

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Programmed Cell Death (Gallus gallus)

- Apoptosis (Gallus gallus)
  - Intrinsic Pathway for Apoptosis (Gallus gallus)
    - Apoptotic factor-mediated response (Gallus gallus)
      - Cytochrome c-mediated apoptotic response (Gallus gallus)
        
        Formation of apoptosome (Gallus gallus)
        
        Regulation of the apoptosome activity (Gallus gallus)
        
        CASP9 is phosphorylated at T125 (Gallus gallus)
        
        APAF1:ATP:CYCS heptamer:p-T125-CASP9 [cytosol] (Gallus gallus)
        
        phospho-CASP9 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:F1NL59

Gene Names

CASP9

Reference Genes

ENSEMBL:ENSGALG00000001366

Other Identifiers

426970

GO:0003674

GO:0004197

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005829

GO:0006508

GO:0006915

GO:0006919

GO:0006950

GO:0006974

GO:0008150

GO:0008219

GO:0008233

GO:0008234

GO:0009411

GO:0042981

GO:0043226

GO:0043525

GO:0071549

GT_A_87_P035288

Gga.4116.1.S1_at

Participates

as a component of

APAF1:ATP:CYCS heptamer:p-T125-CASP9 [cytosol] (Gallus gallus)

Other forms of this molecule

phospho-CASP9 [cytosol]

CASP9 [cytosol]

Inferred From

p-T125-CASP9(1-416) [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 125 (in Homo sapiens)

Coordinate

125

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

OpenTargets

ENSG00000132906

Ensembl

ENSGALG00000001366, ENSGALP00000002083, ENSGALT00000002085

PRO

F1NL59

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