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FAM150B [extracellular region]
Stable Identifier
R-GGA-9842575
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
extracellular region
Synonyms
HC-ALKAL2, A0A1D5PAD6
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ALK (Gallus gallus)
ALK autophosphorylation (Gallus gallus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Gallus gallus)
ligand-bound ALK dimer [plasma membrane] (Gallus gallus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
ligand-bound ALK dimer [plasma membrane] (Gallus gallus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
ALK binds ALKAL ligand (Gallus gallus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK binds PLCG1 (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:PLCG1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK binds SHC1 (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:SHC1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK dimer binds IRS1 (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:IRS1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK phosphorylates IRS1 (Gallus gallus)
Active ALK:IRS1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:pY-IRS1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK phosphorylates PLCG1 (Gallus gallus)
Active ALK:PLCG1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK phosphorylates SHC1 (Gallus gallus)
Active ALK:SHC1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:p-3Y SHC1 [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK recruits PI3K (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Active ALK:PI3K [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
Liganded-ALK dimer binds type I ALK-binding TKIs (Gallus gallus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Gallus gallus)
ligand-bound ALK dimer [plasma membrane] (Gallus gallus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
ligand-bound ALK dimer [plasma membrane] (Gallus gallus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
PI3K synthesizes PIP3 downstream of ALK (Gallus gallus)
Active ALK:PI3K [plasma membrane] (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
STAT3 is phosphorylated downstream of active ALK (Gallus gallus)
Active ALK dimer [plasma membrane] (Gallus gallus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Gallus gallus)
ALKAL2 dimer [extracellular region] (Gallus gallus)
FAM150B [extracellular region] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PAD6
Gene Names
FAM150B
Reference Genes
BioGPS Gene:421910 FAM150B
CTD Gene:421910 FAM150B
ENSEMBL:ENSGALG00000016364
ENSEMBL:ENSGALG00010003837.1 FAM150B
KEGG Gene (Gallus gallus):421910 FAM150B
Monarch:421910 FAM150B
NCBI Gene:421910 FAM150B
Reference Transcript
RefSeq:XM_015284934.1 FAM150B
RefSeq:XM_015284935.1 FAM150B
Other Identifiers
421910
GO:0005125
GO:0005576
GO:0005615
GO:0005886
GO:0007169
GO:0010976
GO:0016020
GO:0023052
GO:0030154
GO:0030297
GO:0030298
GO:0030971
GO:0048018
GO:0048856
GO:0070374
GO:0070378
GO:0098772
GT_A_87_P032540
GgaAffx.10475.1.S1_at
Participates
as a component of
ALKAL2 dimer [extracellular region] (Gallus gallus)
Other forms of this molecule
FAM150B [extracellular region]
Inferred From
HC-ALKAL2 [extracellular region]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via L-cystine (cross-link) at 66 and 66 (in Homo sapiens)
Coordinate
66
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Cross References
RefSeq
XP_015140421.1
,
XP_015140420.1
Ensembl
ENSGALG00010003837
,
ENSGALT00010008875
,
ENSGALP00010005219
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