Reactome | REV (P04618) protein [cytosol]

REV (P04618) protein [cytosol]

Stable Identifier

R-HIV-173267

Type

Protein [EntityWithAccessionedSequence]

Species

Human immunodeficiency virus 1

Compartment

cytosol

GO Cellular Component

host cell cytosol (0044164)

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Locations in the PathwayBrowser for interactor UniProt:Q15363 TMED2

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External Reference Information

External Reference

UniProt:P04618 rev

Gene Names

rev

Chain

chain:1-116

Reference Genes

BioGPS Gene:155908 rev

KEGG:vg:155908 rev

Monarch:155908 rev

NCBI Gene:155908 rev

UCSC:P04618 rev

Reference Transcript

RefSeq:NC_001802.1 env

Participates

as a component of

as an input of

Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)

as an output of

Release of the HIV mRNA and Crm1 from Rev in the cytoplasm (Homo sapiens)

as a repeated unit of

Rev-multimer [cytosol] (Human immunodeficiency virus 1)

Other forms of this molecule

REV (P04618) protein [extracellular region]

REV (P04618) protein [nucleoplasm]

Cross References

PRO

P04618

PDB

6HIP, 7JYA

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04618 rev	3	REV (P04618) protein [extracellular region] (R-HIV-174998) REV (P04618) protein [nucleoplasm] (R-HIV-175380) REV (P04618) protein [cytosol] (R-HIV-173267)	0.618	3
UniProt:O14980 XPO1	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.609	2
UniProt:Q92499-1 DDX1			0.593	6
UniProt:Q04837 SSBP1	1	SSBP1 [mitochondrial matrix] (R-HSA-1592217)	0.558	3
UniProt:Q96BP2 CHCHD1	1	CHCHD1 [mitochondrial inner membrane] (R-HSA-5368208)	0.558	3
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.558	3
UniProt:Q8WV92 MITD1			0.499	2
UniProt:P82933 MRPS9	1	MRPS9 [mitochondrial inner membrane] (R-HSA-5368194)	0.499	2
UniProt:Q15363 TMED2	5	TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-1911531) TMED2 [endoplasmic reticulum membrane] (R-HSA-5689480) TMED2 [ER to Golgi transport vesicle membrane] (R-HSA-5689847) TMED2 [transport vesicle] (R-HSA-6808806) TMED2 [Golgi membrane] (R-HSA-6808804)	0.462	2
UniProt:Q9Y6G3 MRPL42	1	MRPL42 [mitochondrial inner membrane] (R-HSA-5368237)	0.462	2
UniProt:Q7Z7H5 TMED4			0.462	2
UniProt:P49755 TMED10	5	TMED10 [Golgi membrane] (R-HSA-6808801) TMED10 [transport vesicle] (R-HSA-6808802) TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689845) TMED10 [ER to Golgi transport vesicle membrane] (R-HSA-5689843) TMED10 [endoplasmic reticulum membrane] (R-HSA-5689479)	0.462	2
UniProt:Q9BVK6 TMED9	4	TMED9 [endoplasmic reticulum membrane] (R-HSA-6811016) TMED9 [Golgi membrane] (R-HSA-6808813) TMED9 [transport vesicle] (R-HSA-6808878) TMED9 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6807777)	0.462	2
UniProt:Q86XZ4 SPAS2			0.462	2
UniProt:Q9HD23 MRS2	1	MRS2 [mitochondrial inner membrane] (R-HSA-5216072)	0.462	2

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