Reactome | MAFK [nucleoplasm]

MAFK [nucleoplasm]

Stable Identifier

R-HSA-1008242

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor MAFK, MAFK_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60675 MAFK

Gene Names

MAFK

Chain

chain:1-156

Reference Genes

BioGPS Gene:7975 MAFK

COSMIC (genes):MAFK MAFK

CTD Gene:7975 MAFK

dbSNP Gene:7975 MAFK

ENSEMBL:ENSG00000198517 MAFK

HGNC:6782 MAFK

KEGG:hsa:7975 MAFK

Monarch:7975 MAFK

NCBI Gene:7975 MAFK

OMIM:600197 MAFK

UCSC:O60675 MAFK

Reference Transcript

Other Identifiers

11719388_x_at

11719389_a_at

17042895

206750_PM_at

206750_at

226206_PM_at

226206_at

2987202

2987204

2987206

2987207

2987209

2987210

2987213

2987214

2987215

2987216

2987217

2987218

2987220

33014_at

4041505

49188_at

49189_g_at

7975

8131091

A_14_P108538

A_14_P109334

A_14_P122202

A_14_P125897

A_23_P111698

A_23_P373598

GE478482

GE561032

GO:0000122

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001227

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0043226

GO:0043565

GO:0090575

GO:0140110

HMNXSV003006636

Hs.11607.0.A1_3p_at

ILMN_1705986

PH_hs_0001106

PH_hs_0007860

TC07000023.hg

g4505074_3p_at

Participates

as a component of

as an input of

as an output of

as a member of

Small Maf family members [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

AcK-NFE2L2 binds the PDGFA gene (Homo sapiens)

Inferred To

maf-S [nucleoplasm] (Drosophila melanogaster)

Transcription factor MafK [nucleoplasm] (Mus musculus)

MAFK [nucleoplasm] (Bos taurus)

MAFK [nucleoplasm] (Canis familiaris)

MAFK [nucleoplasm] (Gallus gallus)

MAFK [nucleoplasm] (Sus scrofa)

mafk [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_002351.1, XP_006715836.1, XP_005249908.2

ENSEMBL

ENST00000343242, ENSP00000385437, ENSP00000386009, ENST00000406174, ENST00000403150, ENSP00000344903

OpenTargets

ENSG00000198517

HPA

ENSG00000198517-MAFK

PRO

O60675

Pharos - Targets

O60675

GlyGen

O60675

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.806	7
UniProt:Q9BYV9 BACH2			0.666	4
UniProt:O14867 BACH1	5	BACH1 [nucleoplasm] (R-HSA-9707688) BACH1 [cytosol] (R-HSA-9708429) PolyUb-BACH1 [nucleoplasm] (R-HSA-9708486) p-Y483 BACH1 [nucleoplasm] (R-HSA-9762202) p-Y483 BACH1 [cytosol] (R-HSA-9762206)	0.643	4
UniProt:P97302	5	phospho-Bach1 [cytosol] (R-MMU-9762206) phospho-Bach1 [nucleoplasm] (R-MMU-9762202) Bach1 [nucleoplasm] (R-MMU-9708486) Bach1 [cytosol] (R-MMU-9708429) Bach1 [nucleoplasm] (R-MMU-9707688)	0.564	2
UniProt:Q9Y4A8 NF2L3			0.527	2

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