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MX2 [cytosol]
Stable Identifier
R-HSA-1015675
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MXA, Interferon-induced GTP-binding protein Mx2, MX2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
ISGylation of host proteins (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20592 MX2
Gene Names
MX2
Chain
chain:1-715
Reference Genes
BioGPS Gene:4600 MX2
COSMIC (genes):MX2 MX2
CTD Gene:4600 MX2
dbSNP Gene:4600 MX2
ENSEMBL:ENSG00000183486 MX2
HGNC:7533 MX2
KEGG Gene (Homo sapiens):4600 MX2
Monarch:4600 MX2
NCBI Gene:4600 MX2
OMIM:147890 MX2
UCSC:P20592 MX2
Reference Transcript
RefSeq:XM_005260983.4 MX2
RefSeq:XM_011529572.1 MX2
RefSeq:XM_011529571.1 MX2
RefSeq:XM_005260984.1 MX2
RefSeq:NM_002463.1 MX2
Other Identifiers
0006510097
11726479_a_at
11753064_a_at
204994_at
3922038
3922054
3922055
3922056
3922062
3922067
3922072
3922073
3922074
3922075
3922077
3922081
3922085
3922088
3922089
3922090
3922091
3922092
3922093
3922126
4600
8068697
879_at
89899_at
A_14_P119360
A_23_P6263
A_24_P117294
GE57916
GO:0000166
GO:0000266
GO:0002376
GO:0003374
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005643
GO:0005737
GO:0005739
GO:0005829
GO:0005856
GO:0005886
GO:0006810
GO:0006913
GO:0006950
GO:0006952
GO:0007005
GO:0007049
GO:0007165
GO:0008017
GO:0008092
GO:0008150
GO:0009615
GO:0014069
GO:0015031
GO:0015630
GO:0016020
GO:0016185
GO:0016192
GO:0022607
GO:0030424
GO:0031410
GO:0031623
GO:0031966
GO:0032991
GO:0035455
GO:0043167
GO:0043197
GO:0043226
GO:0044327
GO:0045087
GO:0045202
GO:0045211
GO:0046822
GO:0048285
GO:0050803
GO:0051028
GO:0051607
GO:0051726
GO:0060337
GO:0061024
GO:0061025
GO:0065003
GO:0098793
GO:0098844
GO:0098884
ILMN_1754619
ILMN_2231928
M30818_at
PH_hs_0000117
TC21000188.hg
g11342663_3p_at
Participant Of
hasMember
Mx GTPases [cytosol]
Inferred To
mxd [cytosol] (Danio rerio)
mxe [cytosol] (Danio rerio)
mxg [cytosol] (Danio rerio)
mxa [cytosol] (Danio rerio)
Homologues of MX2 [cytosol] (Danio rerio)
Homologues of MX2 [cytosol] (Dictyostelium discoideum)
Homologues of MX2 [cytosol] (Plasmodium falciparum)
dlpA [cytosol] (Dictyostelium discoideum)
shi [cytosol] (Drosophila melanogaster)
mxf [cytosol] (Danio rerio)
MX2 [cytosol] (Bos taurus)
MX2 [cytosol] (Canis familiaris)
MX2 [cytosol] (Plasmodium falciparum)
mxh [cytosol] (Danio rerio)
dymA [cytosol] (Dictyostelium discoideum)
dymB [cytosol] (Dictyostelium discoideum)
dlpB [cytosol] (Dictyostelium discoideum)
mxb [cytosol] (Danio rerio)
mxc [cytosol] (Danio rerio)
mx1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
XP_011527874.1
,
XP_005261041.1
,
XP_011527873.1
,
XP_005261040.1
,
NP_002454.1
OpenTargets
ENSG00000183486
GeneCards
P20592
HPA
ENSG00000183486-MX2
Ensembl
ENST00000330714
,
ENSG00000183486
,
ENSP00000333657
PRO
P20592
PDB
4X0R
,
4WHJ
,
5UOT
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75928 PIAS2
1
PIAS2 [nucleoplasm]
(R-HSA-2993787)
0.556
3
UniProt:Q96KQ7 EHMT2
1
EHMT2 [nucleoplasm]
(R-HSA-212151)
0.556
3
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