Reactome | OAS2 [cytosol]

OAS2 [cytosol]

Stable Identifier

R-HSA-1015689

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

2'-5'-oligoadenylate synthase 2, OAS2_HUMAN

Icon

Locations in the PathwayBrowser for interactor UniProt:P49761

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        OAS2 binds viral dsRNA (Homo sapiens)
        
        OAS2 [cytosol] (Homo sapiens)

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Interferon Signaling (Homo sapiens)
    - Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
      - OAS antiviral response (Homo sapiens)
        
        OAS2 binds viral dsRNA (Homo sapiens)
        
        OAS2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P29728 OAS2

Gene Names

OAS2

Chain

initiator methionine:, chain:2-719

Reference Genes

BioGPS Gene:4939 OAS2

COSMIC (genes):OAS2 OAS2

CTD Gene:4939 OAS2

dbSNP Gene:4939 OAS2

ENSEMBL:ENSG00000111335 OAS2

ENSEMBL_homo_sapiens_GENE:ENSG00000111335.14 OAS2

HGNC:8087 OAS2

KEGG Gene (Homo sapiens):4939 OAS2

Monarch:4939 OAS2

NCBI Gene:4939 OAS2

OMIM:603350 OAS2

UCSC:P29728 OAS2

Reference Transcript

Other Identifiers

11726201_a_at

11726778_at

11736134_a_at

11736135_at

11736136_s_at

16757373

204972_PM_at

204972_at

228607_PM_at

228607_at

3432515

3432516

3432517

3432518

3432519

3432520

3432521

3432522

3432523

3432526

3432527

3432529

3432530

3432531

3432532

3432533

3432534

3432535

3432536

3432537

3432539

3432540

3432541

3432542

3432543

3432544

3432545

3432546

39263_at

39264_at

4939

54823_at

7958913

90662_at

A_14_P112563

A_14_P130941

A_23_P204087

A_24_P343929

A_33_P3225512

A_33_P3225522

GE62523

GE82157

GO:0000166

GO:0001730

GO:0002376

GO:0003723

GO:0003725

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006139

GO:0006401

GO:0009615

GO:0009617

GO:0016020

GO:0016740

GO:0016779

GO:0023052

GO:0032728

GO:0032760

GO:0042742

GO:0043226

GO:0043231

GO:0045071

GO:0045087

GO:0046872

GO:0048471

GO:0048856

GO:0051607

GO:0060337

GO:0070106

GO:0098542

GO:1903487

HMNXSV003007845

HMNXSV003014859

HMNXSV003028387

Hs.99709.0.A1_3p_at

ILMN_1674063

ILMN_1709333

ILMN_1736729

ILMN_2248970

M87434_at

PH_hs_0024977

TC12000886.hg

g8051624_3p_at

Participates

as a component of

OAS2:OAS2 ligand [cytosol] (Homo sapiens)

as an input of

OAS2 binds viral dsRNA (Homo sapiens)

as a member of

OAS proteins [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_058197.2, NP_002526.2, NP_001027903.1

OpenTargets

ENSG00000111335

GeneCards

P29728

HPA

ENSG00000111335-OAS2

Ensembl

ENSP00000411763, ENSP00000376362, ENST00000392583, ENSP00000342278, ENST00000342315, ENST00000449768, ENSG00000111335

PRO

P29728

Pharos - Targets

P29728

Orphanet

28528

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49761 CLK3			0.666	4

Cite Us!