PXLP-K391-ALAS2 [mitochondrial matrix]

Stable Identifier
R-HSA-1022083
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
5-aminolevulinate synthase, erythroid (pyridoxal phosphate cofactor), 5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor, HEM0_HUMAN, ALAS2
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P22557 ALAS2
Gene Names
ALAS2, ALASE, ASB
Chain
transit peptide:1-49, chain:50-587
Reference Genes
BioGPS Gene:212 ALAS2
COSMIC (genes):ALAS2 ALAS2
CTD Gene:212 ALAS2
dbSNP Gene:212 ALAS2
ENSEMBL:ENSG00000158578 ALAS2
HGNC:397 ALAS2
KEGG Gene (Homo sapiens):212 ALAS2
Monarch:212 ALAS2
NCBI Gene:212 ALAS2
OMIM:301300 ALAS2
UCSC:P22557 ALAS2
Reference Transcript
Other Identifiers
0006040022
00260+2.3.1.37
00860+2.3.1.37
11734745_a_at
11738208_a_at
11758412_s_at
1638
17111520
211560_s_at
212
37285_at
4009851
4009852
4009854
4009855
4009858
4009859
4009861
4009862
4009863
4009864
4009866
4009868
4009872
4009873
4009874
4009876
6HRH
8173135
A0A2R8Y6R4
A0A2R8Y782
A0A2R8Y836
A_32_P22654
A_32_P385587
AAC39838
AAH30230
AF068624
AK290565
AK291589
AK313118
AL020991
ALAS2
ALAS2-201
ALAS2-202
ALAS2-209
BAF83254
BAF84278
BAG35939
BC030230
CAA39795
CAA42916
CCDS14366
CCDS35303
CCDS43960
CH471154
EAW93211
EAW93213
ENSG00000158578
ENSP00000337131
ENSP00000379501
ENSP00000497236
ENST00000335854
ENST00000335854.8
ENST00000396198
ENST00000396198.7
ENST00000650242
ENST00000650242.1
EntrezGene:212
EntrezGene:ALAS2
g11493529_3p_s_at
GE59859
GO:0001666
GO:0002376
GO:0003674
GO:0003824
GO:0003870
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005743
GO:0005759
GO:0006778
GO:0006782
GO:0006783
GO:0006879
GO:0006950
GO:0008150
GO:0009058
GO:0016594
GO:0016740
GO:0016746
GO:0030154
GO:0030170
GO:0030218
GO:0032364
GO:0033014
GO:0034641
GO:0042541
GO:0042592
GO:0043167
GO:0043226
GO:0048856
GO:0050662
GO:0051186
H0Y6R3
HGNC:397
HPA001638
ILMN_1708323
ILMN_2271875
ILMN_2367126
IPR001917
IPR004839
IPR010961
IPR015118
IPR015421
IPR015422
IPR015424
LRG_1163
MIM:300751
MIM:300752
MIM:301300
NM_000032
NM_001037967
NM_001037968
NP_000023
NP_001033056
NP_001033057
PF00155
PF09029
PH_hs_0025784
TC0X001077.hg
UPI000012C3FE
UPI000013F1FF
UPI00001AFD0E
X56352
X60364
Z83821
Z83821_cds2_at
Participant Of
hasComponent
Inferred To
Ghost homologue of PXLP-K391-ALAS2 [mitochondrial matrix] (Rattus norvegicus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Bos taurus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Canis familiaris)
PXLP-K391-ALAS2 [mitochondrial matrix] (Danio rerio)
PXLP-K391-ALAS2 [mitochondrial matrix] (Dictyostelium discoideum)
PXLP-K391-ALAS2 [mitochondrial matrix] (Drosophila melanogaster)
PXLP-K391-ALAS2 [mitochondrial matrix] (Gallus gallus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Mus musculus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Plasmodium falciparum)
PXLP-K391-ALAS2 [mitochondrial matrix] (Saccharomyces cerevisiae)
PXLP-K391-ALAS2 [mitochondrial matrix] (Schizosaccharomyces pombe)
PXLP-K391-ALAS2 [mitochondrial matrix] (Sus scrofa)
PXLP-K391-ALAS2 [mitochondrial matrix] (Xenopus tropicalis)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 391
Coordinate
391
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q8N9N5 BANP  1 0.556 3