CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3

Stable Identifier
R-HSA-1028817
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Interaction of CBP/p300 with p-IRF3 dimer
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Phosphorylated IRF3 dimer translocated to the nucleus interacts with the coactivator CBP/p300. This interaction prevents the export of activated IRF3 dimer from nucleus and it may also alter the conformation of the DNA binding domain of IRF3, and induce specific DNA binding of IRF3.

Literature References
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created