Reactome | EGR1 [nucleoplasm]

EGR1 [nucleoplasm]

Stable Identifier

R-HSA-1031703

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Early growth response protein 1, EGR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P18146 EGR1

Gene Names

EGR1, KROX24, ZNF225

Chain

chain:1-543

Reference Genes

BioGPS Gene:1958 EGR1

COSMIC (genes):EGR1 EGR1

COSMIC (genes):ZNF225 EGR1

CTD Gene:1958 EGR1

dbSNP Gene:1958 EGR1

ENSEMBL:ENSG00000120738 EGR1

HGNC:3238 EGR1

KEGG:hsa:1958 EGR1

Monarch:1958 EGR1

NCBI Gene:1958 EGR1

OMIM:128990 EGR1

UCSC:P18146 EGR1

Reference Transcript

RefSeq:NM_001964.2 EGR1

Other Identifiers

11717860_a_at

11717861_a_at

11717862_x_at

11751643_x_at

11752940_a_at

11754334_s_at

16989736

1958

201693_PM_s_at

201693_s_at

201694_PM_s_at

201694_s_at

2830871

2830872

2830873

2830874

2830875

2830878

2830879

2830880

2830881

2830882

2830883

2830884

2830885

2830886

2830887

2830888

2830889

2830890

2830891

789_at

8108370

A_23_P214080

GE81094

GO:0000122

GO:0000785

GO:0000976

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0001666

GO:0002376

GO:0002931

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006325

GO:0006355

GO:0006357

GO:0008270

GO:0009749

GO:0010385

GO:0010628

GO:0019899

GO:0022414

GO:0030154

GO:0030217

GO:0030509

GO:0032722

GO:0032731

GO:0032868

GO:0032922

GO:0033233

GO:0035035

GO:0035914

GO:0042981

GO:0043226

GO:0043523

GO:0043565

GO:0044029

GO:0044729

GO:0044849

GO:0045475

GO:0045893

GO:0045944

GO:0046872

GO:0046886

GO:0048511

GO:0060086

GO:0070498

GO:0071480

GO:0071504

GO:0071506

GO:0072110

GO:0072303

GO:0090090

GO:0098759

GO:0140110

GO:1901875

GO:1902895

GO:1990837

GO:1990841

GO:2000182

HMNXSV003040192

Hs.326035.0.A1_3p_a_at

ILMN_1762899

PH_hs_0016176

TC05000701.hg

X52541_at

g4503492_3p_a_at

Participates

as an output of

as a member of

as an input of

as a component of

Inferred To

Egr1 [nucleoplasm] (Mus musculus)

Egr1 [nucleoplasm] (Rattus norvegicus)

sr [nucleoplasm] (Drosophila melanogaster)

egr1 [nucleoplasm] (Danio rerio)

egr1 [nucleoplasm] (Xenopus tropicalis)

egrh-1 [nucleoplasm] (Caenorhabditis elegans)

EGR1 [nucleoplasm] (Bos taurus)

EGR1 [nucleoplasm] (Canis familiaris)

EGR1 [nucleoplasm] (Gallus gallus)

EGR1 [nucleoplasm] (Sus scrofa)

CRZ1 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001955.1

ENSEMBL

ENSP00000239938, ENST00000239938

OpenTargets

ENSG00000120738

HPA

ENSG00000120738-EGR1

PRO

P18146

Pharos - Targets

P18146

GlyGen

P18146

PDB

4R2D, 4R2C, 4R2A, 5N14, 4X9J

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q504T8 MIDN			0.527	2
UniProt:Q8N726 CDKN2A	12	p14ARF [nucleoplasm] (R-HSA-1629813) p14ARF [cytosol] (R-HSA-9645669) p14ARF [mitochondrial matrix] (R-HSA-9645695) p14ARF R98L;R99S [cytosol] (R-HSA-9645730) p14ARF R82C [cytosol] (R-HSA-9645750) p14ARF R90H [cytosol] (R-HSA-9645755) p14ARF R88Q [cytosol] (R-HSA-9645754) p14ARF R87C [cytosol] (R-HSA-9645759) p14ARF R81G [cytosol] (R-HSA-9645741) p14ARF R98Q [cytosol] (R-HSA-9645757) p14ARF R99C [cytosol] (R-HSA-9645756) p14ARF V22Pfs*46 [cytosol] (R-HSA-9646285)	0.524	4
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926) p-Y-CTNNB1 [cytosol] (R-HSA-8876940)	0.499	7

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