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TFIIE [nucleoplasm]
Stable Identifier
R-HSA-109633
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV Promoter Opening: First Transition (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV Transcription Initiation (Homo sapiens)
Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Newly formed phosphodiester bond stabilized and PPi released (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Abortive HIV-1 Initiation After Second Transition (Homo sapiens)
HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Abortive HIV-1 Initiation Before Second Transition (Homo sapiens)
HIV-1 Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript: Second Transition (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Abortive Initiation After Second Transition (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Abortive Initiation Before Second Transition (Homo sapiens)
Pol II Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Abortive initiation after formation of the first phosphodiester bond (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
RNA Polymerase II Promoter Escape (Homo sapiens)
Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent transcript (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Unwinding DNA for the nascent transcript (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the Nascent Transcript: Second Transition (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA Polymerase II Promoter Opening: First Transition (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation (Homo sapiens)
NTP Binds Active Site of RNA Polymerase II (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Homo sapiens)
Binding of TFIIE to the growing preinitiation complex (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Formation of the closed pre-initiation complex (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Integrator complex processes the 3' end of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
TFIIE [nucleoplasm] (Homo sapiens)
Participants
components
GTF2E1 [nucleoplasm]
(Homo sapiens)
GTF2E2 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
HIV-1 Promoter Escape Complex [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
Pol II Promoter Escape Complex [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Homo sapiens)
as an input of
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)
Binding of TFIIE to the growing preinitiation complex (Homo sapiens)
as an output of
Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)
Abortive HIV-1 Initiation Before Second Transition (Homo sapiens)
Abortive Initiation Before Second Transition (Homo sapiens)
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (Homo sapiens)
Abortive HIV-1 Initiation After Second Transition (Homo sapiens)
Abortive Initiation After Second Transition (Homo sapiens)
Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)
Abortive initiation after formation of the first phosphodiester bond (Homo sapiens)
Inferred To
TFIIE [nucleoplasm]
(Bos taurus)
TFIIE [nucleoplasm]
(Caenorhabditis elegans)
TFIIE [nucleoplasm]
(Canis familiaris)
TFIIE [nucleoplasm]
(Danio rerio)
TFIIE [nucleoplasm]
(Dictyostelium discoideum)
TFIIE [nucleoplasm]
(Drosophila melanogaster)
TFIIE [nucleoplasm]
(Gallus gallus)
TFIIE [nucleoplasm]
(Mus musculus)
TFIIE [nucleoplasm]
(Plasmodium falciparum)
TFIIE [nucleoplasm]
(Rattus norvegicus)
TFIIE [nucleoplasm]
(Saccharomyces cerevisiae)
TFIIE [nucleoplasm]
(Schizosaccharomyces pombe)
TFIIE [nucleoplasm]
(Sus scrofa)
TFIIE [nucleoplasm]
(Xenopus tropicalis)
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