Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex

Stable Identifier
R-HSA-109638
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The general transcription factor TFIIF has a high affinity for the RNA Polymerase II holoenzyme. TFIIF stabilizes the preinitiation complex, and suppresses non-specific binding of RNA Pol II to DNA, and is thus critical for start site recognition.

Literature References
PubMed ID Title Journal Year
8946909 The general transcription factors of RNA polymerase II.

Orphanides, G, Lagrange, T, Reinberg, D

Genes Dev 1997
Participants
Participant Of
Orthologous Events
Authored
Created