PKB-mediated events

Stable Identifier
R-HSA-109703
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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PKB and PDK1 are activated via membrane-bound PIP3. Activated PDK1 phosphorylates PKB, which in turn phosphorylates PDE3B. The latter hydrolyses cAMP to 5'AMP, depleting cAMP pools.
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Orthologous Events
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