Displacement of UNG glycosylase by APEX1 at the AP site

Stable Identifier
R-HSA-110349
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

APEX1 (APE1, HAP1), a DNA apurinic/apyrimidinic (AP) site lyase, displaces UNG from the AP site generated by UNG DNA glycosylase activity (Nicholl et al. 1997, Parikh et al. 1998, Akbari et al. 2004, Kuznetsova et al. 2014).

Participants
Participant Of
Orthologous Events
Authored
Reviewed