Displacement of DNA glycosylase by APEX1

Stable Identifier
R-HSA-110357
Type
Pathway
Species
Homo sapiens
Compartment
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Following cleavage of the damaged base, DNA glycosylase is displaced by APEX1, an AP endonuclease (Parikh et al. 1998).

Literature References
PubMed ID Title Journal Year
9724657 Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA

Parikh, SS, Mol, CD, Slupphaug, G, Bharati, S, Krokan, HE, Tainer, JA

EMBO J 1998
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Orthologous Events
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