p-Y1034-JAK1 [cytosol]

Stable Identifier
R-HSA-1112543
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p(Y1034)-JAK1, Tyrosine-protein kinase JAK1, JAK1_HUMAN, Janus kinase 1
Icon
p-Y1034-JAK1 [cytosol] icon
p-Y1034-JAK1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P23458 JAK1
Gene Names
JAK1, JAK1A, JAK1B
Chain
chain:1-1154
Reference Genes
BioGPS Gene:3716 JAK1
COSMIC (genes):JAK1 JAK1
CTD Gene:3716 JAK1
dbSNP Gene:3716 JAK1
ENSEMBL:ENSG00000162434 JAK1
HGNC:6190 JAK1
KEGG:hsa:3716 JAK1
Monarch:3716 JAK1
NCBI Gene:3716 JAK1
OMIM:147795 JAK1
UCSC:P23458 JAK1
Reference Transcript
Other Identifiers
11717685_at
11717686_a_at
11717687_a_at
1457_at
1552610_PM_a_at
1552610_a_at
1552611_PM_a_at
1552611_a_at
16688164
16688214
17120092
17120096
201648_PM_at
201648_at
239695_PM_at
239695_at
2416521
2416523
2416524
2416525
2416526
2416528
2416529
2416530
2416531
2416532
2416534
2416535
2416536
2416537
2416538
2416539
2416540
2416541
2416542
2416544
2416545
2416549
2416550
2416551
2416552
2416553
2416556
2416558
2416559
2416560
2416561
2416562
2416563
2416564
2416566
2416568
2416569
2416570
2416593
2416594
2416595
2416602
2416607
2416609
2416611
2416692
2416709
2416711
34877_at
3716
41594_at
7916747
82666_at
A_21_P0001139
A_21_P0010619
A_21_P0010621
A_21_P0010623
A_21_P0010761
A_23_P97005
A_24_P410678
A_33_P3784283
GE58033
GE725934
GE746360
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005131
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005768
GO:0005829
GO:0005856
GO:0005886
GO:0005925
GO:0006468
GO:0007259
GO:0009898
GO:0012505
GO:0016020
GO:0016740
GO:0019221
GO:0019903
GO:0030154
GO:0030155
GO:0031234
GO:0031410
GO:0031625
GO:0031730
GO:0034112
GO:0035556
GO:0035723
GO:0035771
GO:0038110
GO:0038111
GO:0038113
GO:0038154
GO:0038196
GO:0043226
GO:0046677
GO:0046872
GO:0051239
GO:0060333
GO:0060337
GO:0060397
GO:0070102
GO:0072540
GO:0098586
GO:0140096
GO:0140105
GO:0150105
GO:1900182
GO:1903672
HMNXSV003011048
HMNXSV003020647
HMNXSV003057545
Hs.144848.0.A1_3p_at
Hs.50651.0.S2_3p_at
Hs2.398570.1.S1_3p_at
Hs2.50651.1.S1_3p_s_at
Hs2.50651.1.S2_3p_s_at
ILMN_1793384
M64174_at
PH_hs_0025462
PH_hs_0039571
TC01002741.hg
TC01002742.hg
TC01002747.hg
TC01005539.hg
TC01005542.hg
p232
p25648
p28938
Participates
as a member of
Other forms of this molecule
p-Y-JAK1 [cytosol]
JAK1 [cytosol]
p-JAK1 [cytosol]
JAK1 [endosome]
p-Y1034,Y1035-JAK1 [cytosol]
Inferred To
phospho-p-Y1034-JAK1 [cytosol] (Bos taurus)
phospho-p-Y1034-JAK1 [cytosol] (Danio rerio)
phospho-p-Y1034-JAK1 [cytosol] (Mus musculus)
phospho-p-Y1034-JAK1 [cytosol] (Rattus norvegicus)
phospho-p-Y1034-JAK1 [cytosol] (Sus scrofa)
phospho-p-Y1034-JAK1 [cytosol] (Xenopus tropicalis)
phospho-JAK1 [cytosol] (Canis familiaris)
phospho-JAK1 [cytosol] (Gallus gallus)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1034
Coordinate
1034
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
HPA
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (18)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42224 STAT1  8 0.757 6
 UniProt:P48551 IFNAR2      0.591 3
 UniProt:Q99650 OSMR  1 0.564 2
 UniProt:P40763 STAT3  12 0.564 2
 UniProt:P40189-1 IL6ST  1 0.556 3
 UniProt:Q14627 IL13RA2  1 0.527 2
 UniProt:P24394 IL4R  2 0.527 2
 UniProt:P37173 TGFBR2  9 0.527 3
 UniProt:Q9UQV4 LAMP3      0.527 2
 UniProt:P15260 IFNGR1  2 0.527 2
 UniProt:P43657 LPAR6  1 0.527 2
 UniProt:P04201 MAS      0.527 2
 UniProt:Q8TDQ0 HAVCR2  1 0.527 2
 UniProt:P46059 SLC15A1  1 0.527 2
 UniProt:Q9H8J5 MANS1      0.527 2
 UniProt:P35414 APLNR  1 0.527 3
 UniProt:O75886 STAM2  2 0.502 2
 UniProt:O60674 JAK2  8 0.463 4
Cite Us!