p-Y1054-TYK2 [cytosol]

Stable Identifier
R-HSA-1112598
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p(Y1054)-TYK2, Non-receptor tyrosine-protein kinase TYK2, TYK2_HUMAN
Icon
p-Y1054-TYK2 [cytosol] icon
p-Y1054-TYK2 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P29597 TYK2
Gene Names
TYK2
Chain
chain:1-1187
Reference Genes
BioGPS Gene:7297 TYK2
COSMIC (genes):TYK2 TYK2
CTD Gene:7297 TYK2
dbSNP Gene:7297 TYK2
ENSEMBL:ENSG00000105397 TYK2
HGNC:12440 TYK2
KEGG:hsa:7297 TYK2
Monarch:7297 TYK2
NCBI Gene:7297 TYK2
OMIM:176941 TYK2
UCSC:P29597 TYK2
Reference Transcript
Other Identifiers
11757379_a_at
16868689
205546_PM_s_at
205546_s_at
3850279
3850280
3850281
3850282
3850284
3850285
3850288
3850289
3850290
3850291
3850292
3850293
3850294
3850295
3850296
3850298
3850299
3850300
3850301
3850302
3850303
3850304
3850305
3850306
3850307
3850308
3850309
3850310
3850311
3850312
3850313
3850314
3850315
3850316
3850317
3850318
3850319
3850320
3850321
3850322
3850323
3850325
3850326
3850327
3850328
7297
8033996
993_at
A_23_P141917
A_23_P153311
GE59795
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005131
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0006468
GO:0006955
GO:0007259
GO:0009898
GO:0016020
GO:0016740
GO:0019221
GO:0019897
GO:0030154
GO:0030155
GO:0031234
GO:0031702
GO:0032729
GO:0032740
GO:0032819
GO:0035556
GO:0035722
GO:0038155
GO:0038196
GO:0042022
GO:0042102
GO:0043226
GO:0046427
GO:0051142
GO:0051239
GO:0060333
GO:0060337
GO:0060397
GO:0070062
GO:0072536
GO:0098586
GO:0140096
GO:0140105
GO:1900182
GO:2000318
HMNXSV003025674
ILMN_1676955
PH_hs_0004337
TC19001164.hg
X54637_at
g4507748_3p_a_at
Participates
as a candidate of
Other forms of this molecule
p-Y1054,Y1055-TYK2 [cytosol]
TYK2 [cytosol]
p-Y-TYK2 [cytosol]
p-TYK2 [cytosol]
Inferred To
phospho-TYK2 [cytosol] (Canis familiaris)
phospho-p-Y1054-TYK2 [cytosol] (Bos taurus)
phospho-p-Y1054-TYK2 [cytosol] (Gallus gallus)
phospho-p-Y1054-TYK2 [cytosol] (Mus musculus)
phospho-p-Y1054-TYK2 [cytosol] (Rattus norvegicus)
phospho-p-Y1054-TYK2 [cytosol] (Sus scrofa)
phospho-p-Y1054-TYK2 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1054
Coordinate
1054
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Investigational
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q5VWX1 KHDRBS2  2 0.781 7
 UniProt:Q13643 FHL3      0.718 6
 UniProt:P61978 HNRNPK  2 0.666 4
 UniProt:P52630 STAT2  4 0.641 4
 UniProt:P17181 IFNAR1  2 0.564 2
 UniProt:P17181-1 IFNAR1      0.558 3
 UniProt:A8MQ03 CRTP1      0.556 3
 UniProt:Q15323 KRT31  1 0.556 3
 UniProt:Q6A162 KRT40  1 0.556 3
 UniProt:A6NEM1 GG6L9      0.556 3
 UniProt:O95994 AGR2      0.556 5
 UniProt:Q9BUZ4 TRAF4      0.556 3
 UniProt:O75525 KHDRBS3  2 0.556 3
 UniProt:Q9NQX1-2 PRDM5      0.556 3
 UniProt:P61978-2 HNRNPK      0.556 3
 UniProt:Q9ULX6 AKAP8L  1 0.556 3
 UniProt:Q05BL1 Q05BL1      0.556 3
 UniProt:Q3LI67 KRTAP6-3  1 0.556 3
 UniProt:P24394 IL4R  2 0.527 2
 UniProt:O75496 GMNN  2 0.527 2
 UniProt:Q8IYS4 DAAF8      0.527 2
 UniProt:Q96FV0 LRC46      0.527 2
 UniProt:Q8TDQ0 HAVCR2  1 0.527 2
 UniProt:O43567 RNF13      0.527 3
 UniProt:Q8NFN8 GP156      0.527 2
 UniProt:P55286 CDH8  1 0.527 2
 UniProt:P52799 EFNB2  2 0.527 2
 UniProt:P11912 CD79A  2 0.527 2
 UniProt:P04019 VE6      0.524 3
 UniProt:P08238 HSP90AB1  6 0.524 2
 UniProt:P06463 VE6      0.524 4
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