Formation of phosphoribosyl pyrophosphate amidotransferase tetramer

Stable Identifier
R-HSA-111285
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic AMP, GMP, and IMP stimulate the association of phosphoribosyl pyrophosphate amidotransferase (PPAT) dimers to form tetramers (Holmes et al. 1973a,b).

Literature References
PubMed ID Title Journal Year
4726295 Human glutamine phosphoribosylpyrophosphate amidotransferase. Two molecular forms interconvertible by purine ribonucleotides and phosphoribosylpyrophosphate

Holmes, EW, Wyngaarden, JB, Kelley, WN

J Biol Chem 1973
4348202 Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties

Holmes, EW, McDonald, JA, McCord, JM, Wyngaarden, JB, Kelley, WN

J Biol Chem 1973
Participants
Participant Of
This event is regulated
Orthologous Events
Created
Cite Us!