SMAC, XIAP-regulated apoptotic response

Stable Identifier
R-HSA-111469
Type
Pathway
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser
Once released from the mitochondria, SMAC binds to IAP family proteins displacing them from Caspase:IAP complexes liberating the active caspases.
Literature References
PubMed ID Title Journal Year
15077149 Toxic proteins released from mitochondria in cell death

van Loo, G, van Gurp, M, Vandenabeele, P, Saelens, X, Vande Walle, L, Festjens, N

Oncogene 2004
Participants
Participates
Orthologous Events
Cross References
Authored
Reviewed
Created
Cite Us!