Reactome | G-betagamma [plasma membrane]

G-betagamma [plasma membrane]

Stable Identifier

R-HSA-111865

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Leishmania parasite growth and survival (Homo sapiens)
        
        Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        FCGR3A-mediated IL10 synthesis (Homo sapiens)
        
        Adenylate cyclase produces cAMP (Homo sapiens)
        
        G-betagamma [plasma membrane] (Homo sapiens)

Signal Transduction (Homo sapiens)

- Intracellular signaling by second messengers (Homo sapiens)
  - DAG and IP3 signaling (Homo sapiens)
    - CaM pathway (Homo sapiens)
      - Calmodulin induced events (Homo sapiens)
        
        PKA-mediated phosphorylation of CREB (Homo sapiens)
        
        PKA activation (Homo sapiens)
        
        Adenylate cyclase produces cAMP (Homo sapiens)
        
        G-betagamma [plasma membrane] (Homo sapiens)
- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Opioid Signalling (Homo sapiens)
        
        G-protein mediated events (Homo sapiens)
        
        PLC beta mediated events (Homo sapiens)
        
        Ca-dependent events (Homo sapiens)
        
        CaM pathway (Homo sapiens)
        
        Calmodulin induced events (Homo sapiens)
        
        PKA-mediated phosphorylation of CREB (Homo sapiens)
        
        PKA activation (Homo sapiens)
        
        Adenylate cyclase produces cAMP (Homo sapiens)
        
        G-betagamma [plasma membrane] (Homo sapiens)

This entity regulates

Negatively

Adenylate cyclase produces cAMP (Homo sapiens)

Cross References

ChEBI

36080

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