Reactome | p-S12,S13,T200-CAMK4 [nucleoplasm]

p-S12,S13,T200-CAMK4 [nucleoplasm]

Stable Identifier

R-HSA-111902

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

phospho-CaMK IV

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External Reference Information

External Reference

UniProt:Q16566 CAMK4

Gene Names

CAMK4, CAMK, CAMK-GR, CAMKIV

Chain

chain:1-473

Reference Genes

BioGPS Gene:814 CAMK4

COSMIC (genes):CAMK4 CAMK4

CTD Gene:814 CAMK4

dbSNP Gene:814 CAMK4

ENSEMBL:ENSG00000152495 CAMK4

HGNC:1464 CAMK4

KEGG:hsa:814 CAMK4

Monarch:814 CAMK4

NCBI Gene:814 CAMK4

OMIM:114080 CAMK4

UCSC:Q16566 CAMK4

Reference Transcript

Other Identifiers

11739304_a_at

1421_at

1422_g_at

16987945

210349_PM_at

210349_at

229029_PM_at

229029_at

241871_PM_at

241871_at

2823881

2823882

2823883

2823884

2823885

2823886

2823904

2823908

2823910

2823911

2823912

2823916

2823917

2823922

2823923

2823924

2823925

2823932

2823933

2823934

2823935

2823936

2823937

2823938

2823939

2823940

2823941

2823942

2823943

2823944

2823945

2823946

2823947

2823959

2823961

2823963

2823964

2823965

2823966

2823967

2823969

2823971

2823973

2823975

2823977

2823978

2823979

33514_at

46191_at

53694_at

68195_at

8107307

814

A_14_P104648

A_23_P250347

D30742_at

GE57160

GO:0001650

GO:0002250

GO:0002376

GO:0003824

GO:0004672

GO:0004674

GO:0004683

GO:0005516

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0006355

GO:0006468

GO:0006954

GO:0007165

GO:0007616

GO:0009931

GO:0016740

GO:0030154

GO:0033081

GO:0035556

GO:0043011

GO:0043226

GO:0045670

GO:0045893

GO:0050877

GO:0070062

GO:0106310

GO:0140096

HMNXSV003009172

Hs.190146.0.A1_3p_at

Hs.6187.0.A1_3p_at

ILMN_1767168

ILMN_2166582

PH_hs_0020794

PH_hs_0025799

TC05000521.hg

g407005_3p_at

Participates

as a component of

p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Homo sapiens)

Other forms of this molecule

CAMK4 [cytosol]

CAMK4 [nucleoplasm]

p-T200-CAMK4 [nucleoplasm]

Inferred To

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Bos taurus)

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Dictyostelium discoideum)

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Drosophila melanogaster)

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Mus musculus)

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Plasmodium falciparum)

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm] (Rattus norvegicus)

phospho-CAMK4 [nucleoplasm] (Gallus gallus)

Modified Residues

Name

O-phospho-L-serine at 12

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 13

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 200

Coordinate

200

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001735.1, NP_001310304.1, NP_001310303.1

ZINC - World Drugs

KCC4_HUMAN

Guide to Pharmacology - Targets

1955

ENSEMBL

ENSP00000282356, ENST00000282356, ENST00000512453, ENSP00000422634

OpenTargets

ENSG00000152495

ZINC - FDA approved

KCC4_HUMAN

ZINC - Substances

KCC4_HUMAN

ZINC - Biogenic

KCC4_HUMAN

ZINC target

Q16566

PRO

Q16566

GlyGen

Q16566

PDB

2W4O

ZINC - Investigational

KCC4_HUMAN

HPA

ENSG00000152495-CAMK4

Pharos - Targets

Q16566

ZINC - Predictions - Purchasable

KCC4_HUMAN

HMDB Protein

HMDBP01381

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14161 GIT2	1	GIT2 [cytosol] (R-HSA-446034)	0.527	2
UniProt:Q9Y2X7 GIT1	2	GIT1 [cytosol] (R-HSA-430326) p-Y383-GIT1 [cytosol] (R-HSA-3928463)	0.527	2