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Calmodulin induced events
Stable Identifier
R-HSA-111933
Type
Pathway
Species
Homo sapiens
Compartment
plasma membrane
,
nucleoplasm
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
General
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One important physiological role for Calmodulin is the regulation of adenylylcyclases. Four of the nine known adenylylcyclases are calcium sensitive, in particular type 8 (AC8).
Literature References
PubMed ID
Title
Journal
Year
15381755
Why calcium-stimulated adenylyl cyclases?
Storm, DR
,
Ferguson, GD
Physiology (Bethesda)
2004
Participants
Events
PKA-mediated phosphorylation of CREB
(Homo sapiens)
CaMK IV-mediated phosphorylation of CREB
(Homo sapiens)
Cam-PDE 1 activation
(Homo sapiens)
GRK2 binds CALM1:4Ca2+
(Homo sapiens)
PKC phosphorylates GRK2
(Homo sapiens)
Participates
as an event of
CaM pathway (Homo sapiens)
Orthologous Events
Calmodulin induced events (Bos taurus)
Calmodulin induced events (Caenorhabditis elegans)
Calmodulin induced events (Canis familiaris)
Calmodulin induced events (Danio rerio)
Calmodulin induced events (Dictyostelium discoideum)
Calmodulin induced events (Drosophila melanogaster)
Calmodulin induced events (Gallus gallus)
Calmodulin induced events (Mus musculus)
Calmodulin induced events (Plasmodium falciparum)
Calmodulin induced events (Rattus norvegicus)
Calmodulin induced events (Saccharomyces cerevisiae)
Calmodulin induced events (Schizosaccharomyces pombe)
Calmodulin induced events (Sus scrofa)
Calmodulin induced events (Xenopus tropicalis)
Cross References
BioModels Database
BIOMD0000000467
,
BIOMD0000000088
Authored
Jassal, B (2004-03-31)
Le Novere, N (2004-03-31)
Reviewed
Castagnoli, L (2008-11-06)
Created
Schmidt, EE (2004-03-25)
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