Opioid binds MOR

Stable Identifier
R-HSA-112042
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Opioid binds MOR
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The binding of an opiate peptide to the mu opiate receptor stabilises the receptor conformation in a state of high affinity, both for the ligand itself, and for the G-protein.

Literature References
PubMed ID Title Journal Year
7905839 Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment

Wang, JB, Hawkins, AL, Persico, AM, Uhl, GR, Johnson, PS, Griffin, CA

FEBS Lett 1994
Participants
Input
Output
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as an event of
Orthologous Events
Opioid binds MOR (Bos taurus)
Opioid binds MOR (Canis familiaris)
Opioid binds MOR (Danio rerio)
Opioid binds MOR (Gallus gallus)
Opioid binds MOR (Mus musculus)
Opioid binds MOR (Rattus norvegicus)
Opioid binds MOR (Sus scrofa)
Opioid binds MOR (Xenopus tropicalis)
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Schmidt, EE  (2004-04-06)
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