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thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP]

Stable Identifier
R-HSA-112266
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic thymidine phosphorylase (TYMP) catalyzes the reversible reactions of thymine or uracil with 2-deoxy-D-ribose 1-phosphate to form thymidine or deoxyuridine and orthiophosphate. The active form of the enzyme is a homodimer (Desgranges et al. 1981; Norman et al. 2004; Usuki et al. 1992).

Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
transferase activity, transferring pentosyl groups of TYMP dimer [cytosol]
Physical Entity
Activity
Orthologous Events