Recruitment of elongation factors to form elongation complex

Stable Identifier
Reaction [binding]
Homo sapiens
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At the beginning of this reaction, 1 molecule of 'FACT complex', 1 molecule of 'Elongin Complex', 1 molecule of 'Early elongation complex with hyperphosphorylated Pol II CTD', 1 molecule of 'TFIIH', 1 molecule of 'RNA polymerase II elongation factor ELL', and 1 molecule of 'TFIIS protein' are present. At the end of this reaction, 1 molecule of 'Elongation complex' is present.

This reaction takes place in the 'nucleus'.
Literature References
PubMed ID Title Journal Year
17234882 The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

Pickle, L, Jones, KA, Yoh, SM, Evans, RM, Cho, H

Genes Dev. 2007
19952111 DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation

Yamada, T, Yamaguchi, Y, Handa, H, Hisatake, K, Nakamura, M, Chen, Y, Tsugeno, Y, Yamamoto, J

Genes Dev. 2009
26659056 RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

Tang, Z, Yu, M, Roeder, RG, Zhu, J, Ni, T, Nakadai, T, Yang, W

Science 2015
12676794 The RNA polymerase II elongation complex.

Conaway, JW, Shilatifard, A, Conaway, RC

Annu Rev Biochem 2003
Orthologous Events
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