MAPK1 (ERK2) activation

Stable Identifier
R-HSA-112411
Type
Pathway
Species
Homo sapiens
Compartment
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Summation

Mitogen-activated protein kinase kinase MAP2K2 (also known as MEK2) is a dual threonine and tyrosine recognition kinase that phosphorylates and activates MAPK1 (ERK2) (Ohren et al. 2004; Roskoski 2012).

Literature References
PubMed ID Title Journal Year
8131746 Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues

Zheng, CF, Guan, KL

EMBO J 1994
22177953 MEK1/2 dual-specificity protein kinases: structure and regulation

Roskoski, R Jr

Biochem. Biophys. Res. Commun. 2012
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