Formation of Elongin complex

Stable Identifier
R-HSA-112436
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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General
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At the beginning of this reaction, 1 molecule of 'Elongin A1 protein', and 1 molecule of 'Elongin B:C complex' are present. At the end of this reaction, 1 molecule of 'Elongin Complex' is present.

This reaction takes place in the 'nucleus' (Kibel et al. 1995, Aso et al. 1995, Duan et al. 1995).

Literature References
PubMed ID Title Journal Year
7660129 Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

Aso, T, Lane, WS, Conaway, JW, Conaway, RC

Science 1995
7660122 Inhibition of transcription elongation by the VHL tumor suppressor protein

Duan, DR, Pause, A, Burgess, WH, Aso, T, Chen, DY, Garrett, KP, Conaway, RC, Conaway, JW, Linehan, WM, Klausner, RD

Science 1995
7660130 Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

Kibel, A, Iliopoulos, O, DeCaprio, JA, Kaelin, WG

Science 1995
Participants
Participant Of
Orthologous Events
Created