Abortive termination of early transcription elongation by DSIF:NELF

Stable Identifier
R-HSA-113409
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Abortive termination of early transcription elongation by DSIF:NELF
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In the early elongation phase, shorter transcripts typically of ~30 nt in length are generated due to random termination of elongating nascent transcripts. This abortive cessation of elongation has been observed mainly in the presence of DSIF-NELF bound to Pol II complex. (Reviewed in Conaway et al.,2000; Shilatifard et al., 2003 ).
Literature References
PubMed ID Title Journal Year
12676794 The RNA polymerase II elongation complex.

Conaway, JW, Shilatifard, A, Conaway, RC

Annu Rev Biochem 2003
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Authored
Gopinathrao, G  (2004-04-28)
Created
Conaway, JW  (2003-09-11)
Conaway, RC  (2003-09-11)
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