p-S317,S345-CHEK1 [nucleoplasm]

Stable Identifier
R-HSA-113838
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
phospho-Chk1, Serine/threonine-protein kinase Chk1 (EC 2.7.1.-) phosphorylated, Serine/threonine-protein kinase Chk1
p-S317,S345-CHEK1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:P30307 CDC25C
External Reference Information
External Reference
Gene Names
CHEK1, CHK1
Chain
chain:1-476
Other Identifiers
1111
11729663_a_at
11738250_at
11738251_x_at
11745948_a_at
11745949_x_at
11759013_at
16733104
205393_PM_s_at
205393_s_at
205394_PM_at
205394_at
238075_PM_at
238075_at
3354800
3354801
3354802
3354803
3354804
3354805
3354806
3354807
3354808
3354809
3354810
3354811
3354812
3354813
3354814
3354815
3354818
3354822
3354823
3354824
3354826
3354828
3354829
3354830
3354831
3354832
3354833
3354834
3354839
38920_at
50018_at
7945014
A_14_P109041
A_14_P137119
A_23_P116123
A_33_P3349536
GE62458
GO:0000077
GO:0000086
GO:0000166
GO:0000228
GO:0000278
GO:0000781
GO:0000785
GO:0000794
GO:0001833
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006260
GO:0006281
GO:0006310
GO:0006325
GO:0006338
GO:0006468
GO:0006915
GO:0006974
GO:0006997
GO:0007010
GO:0007049
GO:0007095
GO:0010468
GO:0010569
GO:0010972
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0018107
GO:0019904
GO:0023052
GO:0032991
GO:0035402
GO:0035556
GO:0036211
GO:0042127
GO:0042770
GO:0043226
GO:0043231
GO:0044818
GO:0045787
GO:0045814
GO:0045839
GO:0046602
GO:0048856
GO:0070317
GO:0071260
GO:0071310
GO:0071313
GO:0090399
GO:0106310
GO:0140014
GO:0140096
GO:1901796
GO:1902742
GO:2000279
HMNXSV003031264
HMNXSV003055633
Hs.24529.0.A1_3p_at
ILMN_1664630
PH_hs_0022049
TC11003470.hg
g4502802_3p_at
Participates
This entity regulates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 317
Coordinate
317
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 345
Coordinate
345
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P61981 YWHAG  1 0.697 8
 UniProt:P08238 HSP90AB1  6 0.656 3
 UniProt:P30307 CDC25C  8 0.623 2
 UniProt:Q9HCE7-2 SMURF1      0.611 4
 UniProt:Q9HAW4 CLSPN  5 0.602 5
 UniProt:P06400 RB1  20 0.558 3
 UniProt:Q06609 RAD51  2 0.524 3
 UniProt:P38398 BRCA1  20 0.463 3
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