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G13-activated p115-RhoGEF [plasma membrane]
Stable Identifier
R-HSA-114527
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signalling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
G13-activated p115-RhoGEF [plasma membrane] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Homo sapiens)
G13-activated p115-RhoGEF [plasma membrane] (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
G13-activated p115-RhoGEF [plasma membrane] (Homo sapiens)
p115-RhoGEF activation of RHOA (Homo sapiens)
G13-activated p115-RhoGEF [plasma membrane] (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
Rho GTPase cycle (Homo sapiens)
GEFs activate Rho GTPase:GDP (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
G13-activated p115-RhoGEF [plasma membrane] (Homo sapiens)
Participants
components
ARHGEF1 [cytosol] (Homo sapiens)
G-protein alpha (13):GTP [plasma membrane] (Homo sapiens)
Participant Of
output
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF)
hasMember
GEFs [cytosol]
Inferred To
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G13-activated p115-RhoGEF [plasma membrane] (Caenorhabditis elegans)
G13-activated p115-RhoGEF [plasma membrane] (Canis familiaris)
G13-activated p115-RhoGEF [plasma membrane] (Danio rerio)
G13-activated p115-RhoGEF [plasma membrane] (Drosophila melanogaster)
G13-activated p115-RhoGEF [plasma membrane] (Mus musculus)
G13-activated p115-RhoGEF [plasma membrane] (Rattus norvegicus)
G13-activated p115-RhoGEF [plasma membrane] (Xenopus tropicalis)
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