Reactome: A Curated Pathway Database

Rac1 activation of PI3K

Stable Identifier
R-HSA-114542
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

PIP3 produced by PI3K activity is essential for receptor-driven stimulation of Rac activation, but PI3K also lies downstream of Rac, as Rac1 can form a complex with PI3K alpha leading to its activation.

Literature References
Participants
Participant Of
Orthologous Events