PTP1B dephosphorylates GHR

Stable Identifier
R-HSA-1169192
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

PTP1B induces the dephosphorylation of GHR (Pasquali et al. 2003).

Literature References
PubMed ID Title Journal Year
12907755 Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

Pasquali, C, Curchod, ML, Wälchli, S, Espanel, X, Guerrier, M, Arigoni, F, Strous, G, Hooft van Huijsduijnen, R

Mol Endocrinol 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed