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ISG15:UBCH8:ISG15 E3 ligase [cytosol]
Stable Identifier
R-HSA-1169383
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
Competitive inhibition of translation initiation by ISGylated 4EHP (Homo sapiens)
ISGylated 4EHP [cytosol] (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylated 4EHP:mRNA [cytosol] (Homo sapiens)
ISGylated 4EHP [cytosol] (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of E2 conjugating enzymes (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of IRF3 (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of host protein filamin B (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of host proteins (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of protein phosphatase 1 beta (PP2CB) (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of protein translation regulator 4EHP (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylated 4EHP [cytosol] (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
ISGylation of viral protein NS1 (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
Interaction of E3 ligase with ISG15:E2 complex (Homo sapiens)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Homo sapiens)
Participants
components
ISG15 E3 ligases [cytosol] (Homo sapiens)
ISG15:UBCH8 [cytosol] (Homo sapiens)
Participant Of
input
ISGylation of E2 conjugating enzymes
ISGylation of host protein filamin B
ISGylation of host proteins
ISGylation of IRF3
ISGylation of protein phosphatase 1 beta (PP2CB)
ISGylation of protein translation regulator 4EHP
ISGylation of viral protein NS1
output
Interaction of E3 ligase with ISG15:E2 complex
hasComponent
ISGylated 4EHP [cytosol]
Inferred To
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Caenorhabditis elegans)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Canis familiaris)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Danio rerio)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Dictyostelium discoideum)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Drosophila melanogaster)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Gallus gallus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Plasmodium falciparum)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Rattus norvegicus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Sus scrofa)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Xenopus tropicalis)
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