Expression of Leptin

Stable Identifier
R-HSA-1183003
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
extracellular region
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Summation

The Ob gene encoding leptin is transcribed to yield mRNA and translated to yield protein. Expression of leptin is positively regulated by C/EBPalpha (CEBPA, Miller et al. 1996, Melzner et al. 2002) and negatively regulated by PPARG in adipocytes (De Vos et al. 1996).

Literature References
Participants
Input
Output
Participant Of
hasEvent
This entity is regulated by
Negative Regulation
Positive Regulation