Reactome | EHMT1 [nucleoplasm]

Stable Identifier

R-HSA-1183226

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, EHMT1_HUMAN, KMT1D, G9a-like protein 1, GLP1, GLP

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H9B1 EHMT1

Gene Names

EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D

Chain

initiator methionine:, chain:2-1298

Reference Genes

COSMIC (genes):EHMT1 EHMT1

dbSNP Gene:79813 EHMT1

ENSEMBL:ENSG00000181090 EHMT1

Participates

as a member of

as a component of

Inferred To

EHMT1 [nucleoplasm] (Bos taurus)

EHMT1 [nucleoplasm] (Canis familiaris)

EHMT1 [nucleoplasm] (Gallus gallus)

EHMT1 [nucleoplasm] (Mus musculus)

EHMT1 [nucleoplasm] (Sus scrofa)

ehmt1 [nucleoplasm] (Xenopus tropicalis)

Ehmt1 [nucleoplasm] (Rattus norvegicus)

G9a [nucleoplasm] (Drosophila melanogaster)

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96KQ7 EHMT2	1	EHMT2 [nucleoplasm] (R-HSA-212151)	0.725	4
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.725	4
UniProt:Q04207	7	Rela [nucleoplasm] (R-MMU-177676) Rela [cytosol] (R-MMU-168172) phospho-Rela [nucleoplasm] (R-MMU-5624468) phospho-Rela [nucleoplasm] (R-MMU-5660642) Rela [nucleoplasm] (R-MMU-4755466) phospho-Rela [nucleoplasm] (R-MMU-9861499) Rela [nucleoplasm] (R-MMU-8865233)	0.675	5
UniProt:Q13363 CTBP1	3	CTBP1 [nucleoplasm] (R-HSA-212372) polySUMO2,3-K428-CTBP1 [nucleoplasm] (R-HSA-3108226) monoSUMO1-K428-CTBP1 [nucleoplasm] (R-HSA-3108200)	0.643	5
UniProt:P83916 CBX1	1	CBX1 [nucleoplasm] (R-HSA-9653629)	0.643	3
UniProt:Q9D752	1	Mad2l2 [nucleoplasm] (R-MMU-59092)	0.564	2
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.527	2
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.527	2
UniProt:P45973 CBX5	2	CBX5 [nucleoplasm] (R-HSA-994093) monoSUMO1-K84,K-CBX5 [nucleoplasm] (R-HSA-4615849)	0.527	2
UniProt:Q04206 RELA	7	RELA [nucleoplasm] (R-HSA-177676) RELA [cytosol] (R-HSA-168172) p-S276-RELA [nucleoplasm] (R-HSA-5624468) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) p-S536-RELA [nucleoplasm] (R-HSA-9861499) MeK310-RELA [nucleoplasm] (R-HSA-8865233)	0.499	3