Fertilization

Stable Identifier
R-HSA-1187000
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Mammalian fertilization comprises sperm migration through the female reproductive tract, biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct. Although the broad concepts of fertilization are well defined, our understanding of the biochemical mechanisms underlying sperm-egg binding is limited.

Literature References
PubMed ID Title Journal Year
12479616 The state of the union: the cell biology of fertilization Nat Cell Biol 2002
16467268 Analysis of the human sperm proteome Ann N Y Acad Sci 2005
Participants
Participant Of
hasEvent
Event Information
Go Biological Process
Orthologous Events