NOX2 generates superoxide from oxygen

Stable Identifier
R-HSA-1222376
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Macrophage NOX2 is a membrane complex that generates superoxide anions by reduction of oxygen with NADPH (Babior 1999, Dinauer et al. 1991).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
superoxide-generating NADPH oxidase activity of NOX2 complex [phagocytic vesicle membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed