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EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane]
Stable Identifier
R-HSA-1225979
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
EGF:EGFR Dimer:irrevTKIs
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by Overexpressed Wild-Type EGFR in Cancer (Homo sapiens)
Inhibition of Signaling by Overexpressed EGFR (Homo sapiens)
Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers (Homo sapiens)
EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] (Homo sapiens)
Participants
components
Covalent EGFR tyrosine kinase inhibitors [cytosol]
EGF-like ligands:EGFR dimer [plasma membrane]
(Homo sapiens)
Participates
as an output of
Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers (Homo sapiens)
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