HN-EPAS1 [cytosol]

Stable Identifier
R-HSA-1234112
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
hydroxyAsn847-EPAS1, EPAS1 (HIF2A) with hydroxyasparagine-847, Endothelial PAS domain-containing protein 1, EPAS1_HUMAN, HIF2A
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q99814 EPAS1 (HIF2A)
Gene Names
EPAS1 (HIF2A), EPAS1, BHLHE73, HIF2A, MOP2, PASD2
Chain
chain:1-870
Reference Genes
BioGPS Gene:2034 EPAS1 (HIF2A)
COSMIC (genes):EPAS1 EPAS1 (HIF2A)
CTD Gene:2034 EPAS1 (HIF2A)
dbSNP Gene:2034 EPAS1 (HIF2A)
ENSEMBL:ENSG00000116016 EPAS1 (HIF2A)
HGNC:3374 EPAS1 (HIF2A)
KEGG:hsa:2034 EPAS1 (HIF2A)
Monarch:2034 EPAS1 (HIF2A)
NCBI Gene:2034 EPAS1 (HIF2A)
OMIM:603349 EPAS1 (HIF2A)
UCSC:Q99814 EPAS1 (HIF2A)
Reference Transcript
Other Identifiers
11715411_a_at
11715412_a_at
16879721
200878_PM_at
200878_at
200879_PM_s_at
200879_s_at
2034
2480384
2480386
2480387
2480388
2480389
2480390
2480391
2480392
2480420
2480421
2480422
2480424
2480425
2480426
2480427
2480432
2480433
2480434
2480439
2480440
2480441
2480443
2480444
2480445
2480446
2480447
2480448
2480449
2480451
2480453
2480454
2480455
2480456
38230_at
8041781
A_23_P210210
A_23_P430120
GE59478
GE85977
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001223
GO:0001228
GO:0001525
GO:0001666
GO:0001892
GO:0001974
GO:0002027
GO:0002070
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006979
GO:0007005
GO:0007165
GO:0007601
GO:0010467
GO:0016071
GO:0016607
GO:0030097
GO:0030154
GO:0030218
GO:0030324
GO:0042415
GO:0042789
GO:0043129
GO:0043226
GO:0043565
GO:0045944
GO:0046982
GO:0046983
GO:0048625
GO:0048856
GO:0050877
GO:0060586
GO:0061629
GO:0071456
GO:0120162
GO:0140110
GO:2000434
HMNXSV003057173
Hs.8136.0.S2_3p_at
ILMN_1704753
PH_hs_0011816
PH_hs_0021983
TC02000281.hg
U81984_at
g4503576_3p_a_at
Participates
as a member of
Other forms of this molecule
EPAS1 [cytosol]
EPAS1 [nucleoplasm]
2xHP-EPAS1 [cytosol]
2xHP-EPAS1 [nucleoplasm]
Inferred To
epas1 [cytosol] (Xenopus tropicalis)
sima [cytosol] (Drosophila melanogaster)
hif-1 [cytosol] (Caenorhabditis elegans)
Epas1 [cytosol] (Mus musculus)
Epas1 [cytosol] (Rattus norvegicus)
epas1b [cytosol] (Danio rerio)
EPAS1 [cytosol] (Bos taurus)
EPAS1 [cytosol] (Canis familiaris)
EPAS1 [cytosol] (Gallus gallus)
EPAS1 [cytosol] (Sus scrofa)
Modified Residues
Name
monohydroxylated asparagine at 847
Coordinate
847
PsiMod Name
monohydroxylated asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to one of the diastereomeric 3-hydroxy-L-asparagine residues.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P27540 ARNT  1 0.886 8
 UniProt:P40337 VHL  3 0.659 3
 UniProt:Q9GZT9 EGLN1  1 0.635 3
 UniProt:P60228 EIF3E  1 0.602 10
 UniProt:P09467 FBP1  1 0.602 4
 UniProt:Q9BWF3-1 RBM4      0.576 6
 UniProt:Q9Y2K6 USP20  1 0.556 3
 UniProt:O00327-8 BMAL1      0.556 3
 UniProt:Q8WYA1-3 BMAL2      0.556 3
 UniProt:P40818 USP8  2 0.544 2
 UniProt:P84022 SMAD3  20 0.519 2
 UniProt:Q96RK4 BBS4  1 0.508 2
 UniProt:O60573 EIF4E2  1 0.499 2
Cite Us!