EPAS1 [cytosol]

Stable Identifier
R-HSA-1234119
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Endothelial PAS domain-containing protein 1, EPAS1_HUMAN, HIF2A
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q99814 EPAS1 (HIF2A)
Gene Names
EPAS1 (HIF2A), EPAS1, BHLHE73, HIF2A, MOP2, PASD2
Chain
chain:1-870
Reference Genes
BioGPS Gene:2034 EPAS1 (HIF2A)
CTD Gene:2034 EPAS1 (HIF2A)
dbSNP Gene:2034 EPAS1 (HIF2A)
ENSEMBL:ENSG00000116016 EPAS1 (HIF2A)
ENSEMBL_homo_sapiens_GENE:ENSG00000116016.14 EPAS1 (HIF2A)
HGNC:3374 EPAS1 (HIF2A)
KEGG Gene (Homo sapiens):2034 EPAS1 (HIF2A)
Monarch:2034 EPAS1 (HIF2A)
NCBI Gene:2034 EPAS1 (HIF2A)
OMIM:603349 EPAS1 (HIF2A)
UCSC:Q99814 EPAS1 (HIF2A)
Reference Transcript
Other Identifiers
11715411_a_at
11715412_a_at
16879721
200878_PM_at
200878_at
200879_PM_s_at
200879_s_at
2034
2480386
2480387
2480388
2480389
2480390
2480391
2480392
2480420
2480421
2480424
2480425
2480432
2480433
2480434
2480440
2480441
2480443
2480444
2480447
2480448
2480449
2480451
2480453
2480454
2480455
2480456
38230_at
8041781
A_23_P210210
A_23_P430120
GE59478
GE85977
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001223
GO:0001228
GO:0001525
GO:0001666
GO:0001892
GO:0001974
GO:0002027
GO:0002070
GO:0002376
GO:0003013
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006979
GO:0007005
GO:0007165
GO:0007601
GO:0010467
GO:0016071
GO:0016607
GO:0023052
GO:0030097
GO:0030154
GO:0030218
GO:0030324
GO:0036211
GO:0042415
GO:0042789
GO:0043129
GO:0043226
GO:0043565
GO:0045944
GO:0046982
GO:0046983
GO:0048625
GO:0048856
GO:0050877
GO:0055065
GO:0060586
GO:0061629
GO:0071456
GO:0120162
GO:0140110
GO:2000434
HMNXSV003057173
Hs.8136.0.S2_3p_at
ILMN_1704753
PH_hs_0021983
TC02000281.hg
U81984_at
g4503576_3p_a_at
Participates
as a member of
as an input of
This entity regulates
Positively
Other forms of this molecule
HN-EPAS1 [cytosol]
2xHP-EPAS1 [nucleoplasm]
2xHP-EPAS1 [cytosol]
EPAS1 [nucleoplasm]
Inferred To
epas1 [cytosol] (Xenopus tropicalis)
sima [cytosol] (Drosophila melanogaster)
hif-1 [cytosol] (Caenorhabditis elegans)
Epas1 [cytosol] (Mus musculus)
Epas1 [cytosol] (Rattus norvegicus)
epas1b [cytosol] (Danio rerio)
EPAS1 [cytosol] (Bos taurus)
EPAS1 [cytosol] (Canis familiaris)
EPAS1 [cytosol] (Gallus gallus)
EPAS1 [cytosol] (Sus scrofa)
Cross References
RefSeq
Guide to Pharmacology - Targets
ZINC - Substances
GeneCards
HPA
ZINC target
Ensembl
PRO
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
PDB
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P27540 ARNT  1 0.886 8
 UniProt:P40337 VHL  3 0.659 3
 UniProt:Q9GZT9 EGLN1  1 0.635 3
 UniProt:P09467 FBP1  1 0.602 4
 UniProt:P60228 EIF3E  1 0.602 10
 UniProt:Q9BWF3-1 RBM4      0.576 6
 UniProt:Q8WYA1-3 BMAL2      0.556 3
 UniProt:O00327-8 BMAL1      0.556 3
 UniProt:Q9Y2K6 USP20  1 0.556 3
 UniProt:P40818 USP8  2 0.544 2
 UniProt:P84022 SMAD3  20 0.519 2
 UniProt:Q96RK4 BBS4  1 0.508 2
 UniProt:O60573 EIF4E2  1 0.499 2
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